Inhibition of destructive autoimmune arthritis in Fc[gamma]RIIa transgenic mice by small chemical en...
Inhibition of destructive autoimmune arthritis in Fc[gamma]RIIa transgenic mice by small chemical entities
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Author / Creator
Publisher
London: Blackwell Science Ltd
Journal title
Language
English
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Publication information
Publisher
London: Blackwell Science Ltd
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Scope and Contents
Contents
The interaction of immune complexes with the human Fc receptor, FcγRIIa, initiates the release of inflammatory mediators and is implicated in the pathogenesis of human autoimmune diseases, including rheumatoid arthritis and systemic lupus erythematosus, so this FcR is a potential target for therapy. We have used the three-dimensional structure of a...
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Full title
Inhibition of destructive autoimmune arthritis in Fc[gamma]RIIa transgenic mice by small chemical entities
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Record Identifier
TN_cdi_proquest_miscellaneous_20339587
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20339587
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ISSN
0818-9641
E-ISSN
1440-1711
DOI
10.1038/icb.2008.82
