Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related...
Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial
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England: Elsevier Ltd
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English
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England: Elsevier Ltd
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Summary Background Calcitonin gene-related peptide (CGRP) probably has a role in migraine pathophysiology, and antagonism of its receptors might provide treatment without the vasoconstrictor effects of triptans. We aimed to assess the clinical profile of MK-0974 (telcagepant), an orally bioavailable antagonist of CGRP receptor. Methods In a randomi...
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Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial
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TN_cdi_proquest_miscellaneous_20347375
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20347375
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0140-6736
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1474-547X
DOI
10.1016/S0140-6736(08)61626-8