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Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related...

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20347375

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

About this item

Full title

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

Publisher

England: Elsevier Ltd

Journal title

The Lancet (British edition), 2008-12, Vol.372 (9656), p.2115-2123

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

Summary Background Calcitonin gene-related peptide (CGRP) probably has a role in migraine pathophysiology, and antagonism of its receptors might provide treatment without the vasoconstrictor effects of triptans. We aimed to assess the clinical profile of MK-0974 (telcagepant), an orally bioavailable antagonist of CGRP receptor. Methods In a randomi...

Alternative Titles

Full title

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_20347375

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20347375

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(08)61626-8

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