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Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation

Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2037057989

Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation

About this item

Full title

Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2018-05, Vol.557 (7705), p.439-445

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In vertebrate hearts, the ventricular trabecular myocardium develops as a sponge-like network of cardiomyocytes that is critical for contraction and conduction, ventricular septation, papillary muscle formation and wall thickening through the process of compaction
1
. Defective trabeculation leads to embryonic lethality
2

4
or n...

Alternative Titles

Full title

Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2037057989

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2037057989

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0110-6

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