Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons
Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons
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Author / Creator
Chiba, T , Yamada, M , Sasabe, J , Terashita, K , Shimoda, M , Matsuoka, M and Aiso, S
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Elevation of intracranial soluble amyloid-β (Aβ) levels has been implicated in the pathogenesis of Alzheimer's disease (AD). Intracellular events in neurons, which lead to memory loss in AD, however, remain elusive. Humanin (HN) is a short neuroprotective peptide abolishing Aβ neurotoxicity. Recently, we found that HN derivatives activate the Janus...
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Full title
Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons
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TN_cdi_proquest_miscellaneous_20375144
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20375144
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ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/mp.2008.105
