NLRP3 Inflammasome Is Involved in Q-VD-OPH Induced Necroptosis Following Cerebral Ischemia-Reperfusi...
NLRP3 Inflammasome Is Involved in Q-VD-OPH Induced Necroptosis Following Cerebral Ischemia-Reperfusion Injury
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Author / Creator
Teng, Xue , Chen, Weiwei , Liu, Zhihan , Feng, Tao , Li, Hui , Ding, Sheng , Chen, Yonggang , Zhang, Ying , Tang, Xianping and Geng, Deqin
Publisher
New York: Springer US
Journal title
Language
English
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Publisher
New York: Springer US
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Contents
Necroptosis is a manner of caspase-independent cell death,which accounts for delayed ischemic cerebral injury, and can be used as a novel tool to expand the treatment time window in ischemic cerebral injury. Q-VD-OPH, a novel pan caspase inhibitor, has been identified as an inducer of necroptosis. In this study, we determined the optimal dose of Q-...
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Full title
NLRP3 Inflammasome Is Involved in Q-VD-OPH Induced Necroptosis Following Cerebral Ischemia-Reperfusion Injury
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Record Identifier
TN_cdi_proquest_miscellaneous_2045269722
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2045269722
Other Identifiers
ISSN
0364-3190
E-ISSN
1573-6903
DOI
10.1007/s11064-018-2537-4
