Clinical Pharmacokinetics and Pharmacodynamics of Bortezomib
Clinical Pharmacokinetics and Pharmacodynamics of Bortezomib
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Publisher
Cham: Springer International Publishing
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Language
English
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Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
Proteasome inhibitors disrupt multiple pathways in cells and the bone marrow microenvironment, resulting in apoptosis and inhibition of cell-cycle progression, angiogenesis, and proliferation. Bortezomib is a first-in-class proteasome inhibitor approved for the treatment of multiple myeloma and mantle cell lymphoma after one prior therapy. It is al...
Alternative Titles
Full title
Clinical Pharmacokinetics and Pharmacodynamics of Bortezomib
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TN_cdi_proquest_miscellaneous_2045269745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2045269745
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ISSN
0312-5963
E-ISSN
1179-1926
DOI
10.1007/s40262-018-0679-9