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Clinical Pharmacokinetics and Pharmacodynamics of Bortezomib

Clinical Pharmacokinetics and Pharmacodynamics of Bortezomib

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2045269745

Clinical Pharmacokinetics and Pharmacodynamics of Bortezomib

About this item

Full title

Clinical Pharmacokinetics and Pharmacodynamics of Bortezomib

Publisher

Cham: Springer International Publishing

Journal title

Clinical pharmacokinetics, 2019-02, Vol.58 (2), p.157-168

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Proteasome inhibitors disrupt multiple pathways in cells and the bone marrow microenvironment, resulting in apoptosis and inhibition of cell-cycle progression, angiogenesis, and proliferation. Bortezomib is a first-in-class proteasome inhibitor approved for the treatment of multiple myeloma and mantle cell lymphoma after one prior therapy. It is al...

Alternative Titles

Full title

Clinical Pharmacokinetics and Pharmacodynamics of Bortezomib

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2045269745

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2045269745

Other Identifiers

ISSN

0312-5963

E-ISSN

1179-1926

DOI

10.1007/s40262-018-0679-9

How to access this item