Structural basis for signal recognition and transduction by platelet-activating-factor receptor
Structural basis for signal recognition and transduction by platelet-activating-factor receptor
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Author / Creator
Cao, Can , Tan, Qiuxiang , Xu, Chanjuan , He, Lingli , Yang, Linlin , Zhou, Ye , Zhou, Yiwei , Qiao, Anna , Lu, Minmin , Yi, Cuiying , Han, Gye Won , Wang, Xianping , Li, Xuemei , Yang, Huaiyu , Rao, Zihe , Jiang, Hualiang , Zhao, Yongfang , Liu, Jianfeng , Stevens, Raymond C. , Zhao, Qiang , Zhang, Xuejun C. and Wu, Beili
Publisher
New York: Nature Publishing Group US
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English
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Publisher
New York: Nature Publishing Group US
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Contents
Platelet-activating-factor receptor (PAFR) responds to platelet-activating factor (PAF), a phospholipid mediator of cell-to-cell communication that exhibits diverse physiological effects. PAFR is considered an important drug target for treating asthma, inflammation and cardiovascular diseases. Here we report crystal structures of human PAFR in comp...
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Full title
Structural basis for signal recognition and transduction by platelet-activating-factor receptor
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TN_cdi_proquest_miscellaneous_2046605744
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2046605744
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-018-0068-y
