Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume
Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
Dickkopf-1 (DKK1) and sclerostin are antagonists of the Wnt/β-catenin pathway and decreased expression of either results in increased bone formation and mass. As both affect the same signaling pathway, we aimed to elucidate the redundancy and/or compensation of sclerostin and DKK1. Weekly sclerostin antibody (Scl-Ab) was used to treat 9-week-old fe...
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Full title
Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume
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TN_cdi_proquest_miscellaneous_2047292355
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2047292355
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ISSN
0171-967X
E-ISSN
1432-0827
DOI
10.1007/s00223-018-0420-6
