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Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2051661015

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

About this item

Full title

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2018-06, Vol.24 (6), p.770-781

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Patients with metastatic cancer experience a severe loss of skeletal muscle mass and function known as cachexia. Cachexia is associated with poor prognosis and accelerated death in patients with cancer, yet its underlying mechanisms remain poorly understood. Here, we identify the metal-ion transporter ZRT- and IRT-like protein 14 (ZIP14) as a criti...

Alternative Titles

Full title

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2051661015

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2051661015

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-018-0054-2

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