Bcl-x sub(L) induces Drp1-dependent synapse formation in cultured hippocampal neurons
Bcl-x sub(L) induces Drp1-dependent synapse formation in cultured hippocampal neurons
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Li, Hongmei , Chen, Yingbei , Jones, Adrienne F , Sanger, Richard H , Collis, Leon P , Flannery, Richard , McNay, Ewan C , Yu, Tingxi , Schwarzenbacher, Robert , Bossy, Blaise , Bossy-Wetzel, Ella , Bennett, Michael VL , Pypaert, Marc , Hickman, John A , Smith, Peter JS , Hardwick, JMarie and Jonas, Elizabeth A
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English
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Maturation of neuronal synapses is thought to involve mitochondria. Bcl-x sub(L) protein inhibits mitochondria-mediated apoptosis but may have other functions in healthy adult neurons in which Bcl-x sub(L) is abundant. Here, we report that overexpression of Bcl-x sub(L) postsynaptically increases frequency and amplitude of spontaneous miniature syn...
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Full title
Bcl-x sub(L) induces Drp1-dependent synapse formation in cultured hippocampal neurons
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TN_cdi_proquest_miscellaneous_20532524
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20532524
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ISSN
0027-8424
E-ISSN
1091-6490
