The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src
The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Neddylation is a cellular process that covalently conjugates substrate proteins with the small ubiquitin-like molecule NEDD8. As neddylation is required for fast turnover of proteins in proliferating cancer cells, the neddylation process is currently regarded as a potential target for cancer therapy. However, little is known about the role of neddy...
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The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src
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TN_cdi_proquest_miscellaneous_2055616858
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2055616858
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-018-0354-5
