Loss of Bardet-Biedl Syndrome Proteins Alters the Morphology and Function of Motile Cilia in Airway...
Loss of Bardet-Biedl Syndrome Proteins Alters the Morphology and Function of Motile Cilia in Airway Epithelia
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Mutations in a group of genes that contribute to ciliary function cause Bardet-Biedl syndrome (BBS). Most studies of BBS have focused on primary, sensory cilia. Here, we asked whether loss of BBS proteins would also affect motile cilia lining the respiratory tract. We found that BBS genes were expressed in human airway epithelia, and BBS2 and BBS4...
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Loss of Bardet-Biedl Syndrome Proteins Alters the Morphology and Function of Motile Cilia in Airway Epithelia
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TN_cdi_proquest_miscellaneous_20566526
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20566526
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0712327105
