Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S
Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Aortic valve stenosis (AVS) is the most common valvular heart disease in the Western world. Therapy based on apolipoprotein A-I (apoA-I), the major protein component of high-density lipoproteins, results in AVS regression in experimental models. Nevertheless, apoA-I degradation by proteases might lead to suboptimal efficacy of such therapy. An acti...
Alternative Titles
Full title
Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S
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TN_cdi_proquest_miscellaneous_2057133580
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2057133580
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ISSN
0300-8428
E-ISSN
1435-1803
DOI
10.1007/s00395-018-0689-7