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Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S

Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2057133580

Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S

About this item

Full title

Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Basic research in cardiology, 2018-07, Vol.113 (4), p.30-14, Article 30

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Aortic valve stenosis (AVS) is the most common valvular heart disease in the Western world. Therapy based on apolipoprotein A-I (apoA-I), the major protein component of high-density lipoproteins, results in AVS regression in experimental models. Nevertheless, apoA-I degradation by proteases might lead to suboptimal efficacy of such therapy. An acti...

Alternative Titles

Full title

Apolipoprotein A-I proteolysis in aortic valve stenosis: role of cathepsin S

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2057133580

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2057133580

Other Identifiers

ISSN

0300-8428

E-ISSN

1435-1803

DOI

10.1007/s00395-018-0689-7

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