Generation of GTKO Diannan Miniature Pig Expressing Human Complementary Regulator Proteins hCD55 and...
Generation of GTKO Diannan Miniature Pig Expressing Human Complementary Regulator Proteins hCD55 and hCD59 via T2A Peptide-Based Bicistronic Vectors and SCNT
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New York: Springer US
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English
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New York: Springer US
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Pig-to-human organ transplantation has drawn attention in recent years due to the potential use of pigs as an alternative source of human donor organs. While GGTA1 knockout (GTKO) can protect xenografts from hyperacute rejection, complement-dependent cytotoxicity might still contribute to this type of rejection. To prolong the xenograft survival, w...
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Generation of GTKO Diannan Miniature Pig Expressing Human Complementary Regulator Proteins hCD55 and hCD59 via T2A Peptide-Based Bicistronic Vectors and SCNT
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TN_cdi_proquest_miscellaneous_2057135295
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2057135295
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ISSN
1073-6085
E-ISSN
1559-0305
DOI
10.1007/s12033-018-0091-6