Cyclometallated ruthenium catalyst enables late-stage directed arylation of pharmaceuticals
Cyclometallated ruthenium catalyst enables late-stage directed arylation of pharmaceuticals
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Biaryls are ubiquitous core structures in drugs, agrochemicals and organic materials that have profoundly improved many aspects of our society. Although traditional cross-couplings have made practical the synthesis of many biaryls, C–H arylation represents a more attractive and cost-effective strategy for building these structural motifs. Furthermo...
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Cyclometallated ruthenium catalyst enables late-stage directed arylation of pharmaceuticals
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TN_cdi_proquest_miscellaneous_2058504651
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2058504651
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/s41557-018-0062-3
