A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease
A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Alzheimer’s disease (AD) is characterized by beta-amyloid accumulation, phosphorylated tau formation, hyperactivation of glial cells, and neuronal loss. The mechanisms of AD pathogenesis, however, remain poorly understood, partially due to the lack of relevant models that can comprehensively recapitulate multistage intercellular interactions in hum...
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A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease
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TN_cdi_proquest_miscellaneous_2061406019
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2061406019
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-018-0175-4
