Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis
Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis
About this item
Full title
Author / Creator
Benson, Merrill D , Waddington-Cruz, Márcia , Berk, John L , Polydefkis, Michael , Dyck, Peter J , Wang, Annabel K , Planté-Bordeneuve, Violaine , Barroso, Fabio A , Merlini, Giampaolo , Obici, Laura , Scheinberg, Morton , Brannagan, Thomas H , Litchy, William J , Whelan, Carol , Drachman, Brian M , Adams, David , Heitner, Stephen B , Conceição, Isabel , Schmidt, Hartmut H , Vita, Giuseppe , Campistol, Josep M , Gamez, Josep , Gorevic, Peter D , Gane, Edward , Shah, Amil M , Solomon, Scott D , Monia, Brett P , Hughes, Steven G , Kwoh, T. Jesse , McEvoy, Bradley W , Jung, Shiangtung W , Baker, Brenda F , Ackermann, Elizabeth J , Gertz, Morie A and Coelho, Teresa
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
This phase 3 trial tested inotersen, a modified oligonucleotide that targets
TTR
messenger RNA, in the treatment of hereditary transthyretin amyloidosis, a disease in which misfolded transthyretin proteins are deposited in peripheral nerves and other tissues.
Alternative Titles
Full title
Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis
Authors, Artists and Contributors
Author / Creator
Waddington-Cruz, Márcia
Berk, John L
Polydefkis, Michael
Dyck, Peter J
Wang, Annabel K
Planté-Bordeneuve, Violaine
Barroso, Fabio A
Merlini, Giampaolo
Obici, Laura
Scheinberg, Morton
Brannagan, Thomas H
Litchy, William J
Whelan, Carol
Drachman, Brian M
Adams, David
Heitner, Stephen B
Conceição, Isabel
Schmidt, Hartmut H
Vita, Giuseppe
Campistol, Josep M
Gamez, Josep
Gorevic, Peter D
Gane, Edward
Shah, Amil M
Solomon, Scott D
Monia, Brett P
Hughes, Steven G
Kwoh, T. Jesse
McEvoy, Bradley W
Jung, Shiangtung W
Baker, Brenda F
Ackermann, Elizabeth J
Gertz, Morie A
Coelho, Teresa
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2064782220
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2064782220
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1716793
