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Optimizing orthogonality

Optimizing orthogonality

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2073321170

Optimizing orthogonality

About this item

Full title

Optimizing orthogonality

Publisher

London: Nature Publishing Group UK

Journal title

Nature chemistry, 2018-08, Vol.10 (8), p.802-803

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A new pyrrolysyl-tRNA synthetase/
Pyl
tRNA (PylRS/
Pyl
tRNA) pair that is mutually orthogonal to existing PylRS/
Pyl
tRNA pairs has now been discovered and optimized. This system could enable the site-specific incorporation of a greater number of distinct non-canonical amino acids into a protein.

Alternative Titles

Full title

Optimizing orthogonality

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2073321170

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2073321170

Other Identifiers

ISSN

1755-4330,1755-4349

E-ISSN

1755-4349

DOI

10.1038/s41557-018-0115-7

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