PARP3 inhibitors ME0328 and olaparib potentiate vinorelbine sensitization in breast cancer cell line...
PARP3 inhibitors ME0328 and olaparib potentiate vinorelbine sensitization in breast cancer cell lines
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Purpose
PARP-3 is member of the PARP family of poly (ADP-ribose) polymerases involved in ADPribosylation. PARPs are involved in the basic mechanisms of DNA repair. PARP3, a critical player for efficient mitotic progression, is required for the stabilization of the mitotic spindle by regulation of the mitotic components, NuMA and Tankyrase 1.
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Full title
PARP3 inhibitors ME0328 and olaparib potentiate vinorelbine sensitization in breast cancer cell lines
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TN_cdi_proquest_miscellaneous_2075549022
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2075549022
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ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-018-4888-6
