CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway
CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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CRISPR–Cas genome editing creates targeted DNA double-strand breaks (DSBs) that are processed by cellular repair pathways, including the incorporation of exogenous DNA via single-strand template repair (SSTR). To determine the genetic basis of SSTR in human cells, we developed a coupled inhibition-cutting system capable of interrogating multiple ed...
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CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway
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TN_cdi_proquest_miscellaneous_2078579437
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2078579437
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-018-0174-0
