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Structural basis for the modulation of voltage-gated sodium channels by animal toxins

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2078582170

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

About this item

Full title

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-10, Vol.362 (6412)

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

In “excitable” cells, like neurons and muscle cells, a difference in electrical potential is used to transmit signals across the cell membrane. This difference is regulated by opening or closing ion channels in the cell membrane. For example, mutations in human voltage-gated sodium (Na v ) channels are associated with disorders such as chronic pain...

Alternative Titles

Full title

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2078582170

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2078582170

Other Identifiers

ISSN

0036-8075,1095-9203

E-ISSN

1095-9203

DOI

10.1126/science.aau2596

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