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ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20801731

ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

About this item

Full title

ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (19), p.7945-7950

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

IFN-stimulated gene 56 (ISG56) is one of the first identified proteins induced by viruses and type I IFNs. In this study, we identified ISG56 as a virus-induced protein associated with MITA, an adapter protein involved in virus-triggered induction of type I IFNs. Overexpression of ISG56 inhibited Sendai virus-triggered activation of IRF3, NF-κB, an...

Alternative Titles

Full title

ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_20801731

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20801731

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0900818106

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