Mice lacking ganglioside GM3 synthase exhibit complete hearing loss due to selective degeneration of...
Mice lacking ganglioside GM3 synthase exhibit complete hearing loss due to selective degeneration of the organ of Corti
About this item
Full title
Author / Creator
Yoshikawa, Misato , Go, Shinji , Takasaki, Kotaro , Kakazu, Yasuhiro , Ohashi, Mitsuru , Nagafuku, Masakazu , Kabayama, Kazuya , Sekimoto, Junji , Suzuki, Shun-ichi , Takaiwa, Kazutaka , Kimitsuki, Takashi , Matsumoto, Nozomu , Komune, Shizuo , Kamei, Daisuke , Saito, Masaki , Fujiwara, Michihiro , Iwasaki, Katsunori and Inokuchi, Jin-ichi
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
The ganglioside GM3 synthase (SAT-I), encoded by a single-copy gene, is a primary glycosyltransferase for the synthesis of complex gangliosides. In SAT-I null mice, hearing ability, assessed by brainstem auditory-evoked potentials (BAEP), was impaired at the onset of hearing and had been completely lost by 17 days after birth (P17), showing a defor...
Alternative Titles
Full title
Mice lacking ganglioside GM3 synthase exhibit complete hearing loss due to selective degeneration of the organ of Corti
Authors, Artists and Contributors
Author / Creator
Go, Shinji
Takasaki, Kotaro
Kakazu, Yasuhiro
Ohashi, Mitsuru
Nagafuku, Masakazu
Kabayama, Kazuya
Sekimoto, Junji
Suzuki, Shun-ichi
Takaiwa, Kazutaka
Kimitsuki, Takashi
Matsumoto, Nozomu
Komune, Shizuo
Kamei, Daisuke
Saito, Masaki
Fujiwara, Michihiro
Iwasaki, Katsunori
Inokuchi, Jin-ichi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_20810110
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20810110
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0903279106
