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Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior

Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20813122

Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior

About this item

Full title

Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (26), p.10847-10852

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

A single nucleotide polymorphism (SNP) in the human μ-opioid receptor gene (OPRM1 A118G) has been widely studied for its association in a variety of drug addiction and pain sensitivity phenotypes; however, the extent of these adaptations and the mechanisms underlying these associations remain elusive. To clarify the functional mechanisms linking th...

Alternative Titles

Full title

Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_20813122

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20813122

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0901800106

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