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Pivotal Role of the I- sub(2A)-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Mode...

Pivotal Role of the I- sub(2A)-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Mode...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20875121

Pivotal Role of the I- sub(2A)-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Model of Sepsis

About this item

Full title

Pivotal Role of the I- sub(2A)-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Model of Sepsis

Journal title

PloS one, 2009-01, Vol.4 (5), p.e5504-e5504

Language

English

Formats

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Scope and Contents

Contents

Background Norepinephrine (NE) modulates the responsiveness of macrophages to proinflammatory stimuli through the activation of adrenergic receptors (ARs). Being part of the stress response, early increases of NE in sepsis sustain adverse systemic inflammatory responses. The intestine is an important source of NE release in the early stage of cecal...

Alternative Titles

Full title

Pivotal Role of the I- sub(2A)-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Model of Sepsis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_20875121

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20875121

Other Identifiers

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0005504

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