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11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Development by Lentiviral Screening Based on Compu...

11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Development by Lentiviral Screening Based on Compu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2087993851

11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Development by Lentiviral Screening Based on Computational Modeling

About this item

Full title

11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Development by Lentiviral Screening Based on Computational Modeling

Publisher

Basel, Switzerland

Journal title

Pharmacology, 2018-09, Vol.102 (3-4), p.169-179

Language

English

Formats

Publication information

Publisher

Basel, Switzerland

Subjects

Subjects and topics

More information

Scope and Contents

Contents

In this study, rat and human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) have been cloned by lentiviral transduction and expressed by CHO-K1 cells. The results showed that recombinant plasmids contained R11bhsd1 or H11bhsd1 have been constructed, which is consistent with the gene bank respectively. A clone cell was selected with G418 and cul...

Alternative Titles

Full title

11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Development by Lentiviral Screening Based on Computational Modeling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2087993851

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2087993851

Other Identifiers

ISSN

0031-7012

E-ISSN

1423-0313

DOI

10.1159/000491397

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