11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Development by Lentiviral Screening Based on Compu...
11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Development by Lentiviral Screening Based on Computational Modeling
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Author / Creator
Liu, Haifeng , Li, Lingyu , Zhang, Chunlei , Li, Hongzhi , Liu, Jieting , Tang, Chunyin , Zhang, Yufei , Wu, Dan , Chu, Yanhui , Wu, Yan and Yuan, Xiaohuan
Publisher
Basel, Switzerland
Journal title
Language
English
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Publisher
Basel, Switzerland
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Contents
In this study, rat and human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) have been cloned by lentiviral transduction and expressed by CHO-K1 cells. The results showed that recombinant plasmids contained R11bhsd1 or H11bhsd1 have been constructed, which is consistent with the gene bank respectively. A clone cell was selected with G418 and cul...
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Full title
11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Development by Lentiviral Screening Based on Computational Modeling
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Record Identifier
TN_cdi_proquest_miscellaneous_2087993851
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2087993851
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ISSN
0031-7012
E-ISSN
1423-0313
DOI
10.1159/000491397