Sorafenib plus topotecan versus placebo plus topotecan for platinum-resistant ovarian cancer (TRIAS)...
Sorafenib plus topotecan versus placebo plus topotecan for platinum-resistant ovarian cancer (TRIAS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
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Author / Creator
Chekerov, Radoslav, MD , Hilpert, Felix, Prof , Mahner, Sven, Prof , El-Balat, Ahmed, MD , Harter, Philipp, MD , De Gregorio, Nikolaus, MD , Fridrich, Claudius, MD , Markmann, Susanne, MD , Potenberg, Jochem, MD , Lorenz, Ralf, MD , Oskay-Oezcelik, Guelten, MD , Schmidt, Marcus, MD , Krabisch, Petra, MD , Lueck, Hans-Joachim, Prof , Richter, Rolf, PhD , Braicu, Elena Ioana, Prof , du Bois, Andreas, Prof , Sehouli, Jalid, Prof , NOGGO and AGO TRIAS Investigators
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Contents
SummaryBackgroundAntiangiogenic therapy has known activity in ovarian cancer. The investigator-initiated randomised phase 2 TRIAS trial assessed the multi-kinase inhibitor sorafenib combined with topotecan and continued as maintenance therapy for platinum-resistant or platinum-refractory ovarian cancer. MethodsWe did a multicentre, double-blind, pl...
Alternative Titles
Full title
Sorafenib plus topotecan versus placebo plus topotecan for platinum-resistant ovarian cancer (TRIAS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Hilpert, Felix, Prof
Mahner, Sven, Prof
El-Balat, Ahmed, MD
Harter, Philipp, MD
De Gregorio, Nikolaus, MD
Fridrich, Claudius, MD
Markmann, Susanne, MD
Potenberg, Jochem, MD
Lorenz, Ralf, MD
Oskay-Oezcelik, Guelten, MD
Schmidt, Marcus, MD
Krabisch, Petra, MD
Lueck, Hans-Joachim, Prof
Richter, Rolf, PhD
Braicu, Elena Ioana, Prof
du Bois, Andreas, Prof
Sehouli, Jalid, Prof
NOGGO
AGO TRIAS Investigators
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2087994681
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2087994681
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(18)30372-3
