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Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2088295174

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

About this item

Full title

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2018-09, Vol.21 (9), p.1218-1228

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Autism spectrum disorders (ASDs) are four times more common in males than in females, but the underlying mechanisms are poorly understood. We characterized sexually dimorphic changes in mice carrying a heterozygous mutation in
Chd8
(
Chd8
+/N2373K
) that was first identified in human
CHD8
(Asn2373LysfsX2), a strong ASD-risk gen...

Alternative Titles

Full title

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2088295174

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2088295174

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/s41593-018-0208-z

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