Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice
Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice
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Author / Creator
Jung, Hwajin , Park, Haram , Choi, Yeonsoo , Kang, Hyojin , Lee, Eunee , Kweon, Hanseul , Roh, Junyeop Daniel , Ellegood, Jacob , Choi, Woochul , Kang, Jaeseung , Rhim, Issac , Choi, Su-Yeon , Bae, Mihyun , Kim, Sun-Gyun , Lee, Jiseok , Chung, Changuk , Yoo, Taesun , Park, Hanwool , Kim, Yangsik , Ha, Seungmin , Um, Seung Min , Mo, Seojung , Kwon, Yonghan , Mah, Won , Bae, Yong Chul , Kim, Hyun , Lerch, Jason P , Paik, Se-Bum and Kim, Eunjoon
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Autism spectrum disorders (ASDs) are four times more common in males than in females, but the underlying mechanisms are poorly understood. We characterized sexually dimorphic changes in mice carrying a heterozygous mutation in
Chd8
(
Chd8
+/N2373K
) that was first identified in human
CHD8
(Asn2373LysfsX2), a strong ASD-risk gen...
Alternative Titles
Full title
Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice
Authors, Artists and Contributors
Author / Creator
Park, Haram
Choi, Yeonsoo
Kang, Hyojin
Lee, Eunee
Kweon, Hanseul
Roh, Junyeop Daniel
Ellegood, Jacob
Choi, Woochul
Kang, Jaeseung
Rhim, Issac
Choi, Su-Yeon
Bae, Mihyun
Kim, Sun-Gyun
Lee, Jiseok
Chung, Changuk
Yoo, Taesun
Park, Hanwool
Kim, Yangsik
Ha, Seungmin
Um, Seung Min
Mo, Seojung
Kwon, Yonghan
Mah, Won
Bae, Yong Chul
Kim, Hyun
Lerch, Jason P
Paik, Se-Bum
Kim, Eunjoon
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2088295174
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2088295174
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-018-0208-z