Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose
Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose
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Author / Creator
Zhou, Ping , She, Yang , Dong, Na , Li, Peng , He, Huabin , Borio, Alessio , Wu, Qingcui , Lu, Shan , Ding, Xiaojun , Cao, Yong , Xu, Yue , Gao, Wenqing , Dong, Mengqiu , Ding, Jingjin , Wang, Da-Cheng , Zamyatina, Alla and Shao, Feng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Immune recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors often activates proinflammatory NF-κB signalling
1
. Recent studies indicate that the bacterial metabolite
d
-glycero-β-
d
-manno-heptose 1,7-bisphosphate (HBP) can activate NF-κB signalling in host cytosol
2
–
4
, but...
Alternative Titles
Full title
Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose
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Record Identifier
TN_cdi_proquest_miscellaneous_2089283754
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2089283754
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0433-3
