Hematopoietic-Specific Lentiviral Vectors Circumvent Cellular Toxicity Due to Ectopic Expression of...
Hematopoietic-Specific Lentiviral Vectors Circumvent Cellular Toxicity Due to Ectopic Expression of Wiskott-Aldrich Syndrome Protein
About this item
Full title
Author / Creator
Publisher
Larchmont, NY: Liebert
Journal title
Language
English
Formats
Publication information
Publisher
Larchmont, NY: Liebert
Subjects
More information
Scope and Contents
Contents
Efficient and safe gene modification of hematopoietic stem cells is a requirement for gene therapy of primary immunodeficiencies such as Wiskott-Aldrich syndrome. However, deregulated expression or ectopic expression in the progeny of transduced nonhematopoietic progenitor cells may lead to unwanted toxicity. We therefore analyzed the effect of ect...
Alternative Titles
Full title
Hematopoietic-Specific Lentiviral Vectors Circumvent Cellular Toxicity Due to Ectopic Expression of Wiskott-Aldrich Syndrome Protein
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_20893471
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20893471
Other Identifiers
ISSN
1043-0342
E-ISSN
1557-7422
DOI
10.1089/hum.2007.098
