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Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2091240254

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent

About this item

Full title

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2018-10, Vol.24 (10), p.1579-1589

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Amyotrophic lateral sclerosis (ALS) is a heterogeneous motor neuron disease for which no effective treatment is available, despite decades of research into
SOD1
-mutant familial ALS (FALS). The majority of ALS patients have no familial history, making the modeling of sporadic ALS (SALS) essential to the development of ALS therapeutics. Howeve...

Alternative Titles

Full title

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2091240254

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2091240254

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-018-0140-5

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