Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent
Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Amyotrophic lateral sclerosis (ALS) is a heterogeneous motor neuron disease for which no effective treatment is available, despite decades of research into
SOD1
-mutant familial ALS (FALS). The majority of ALS patients have no familial history, making the modeling of sporadic ALS (SALS) essential to the development of ALS therapeutics. Howeve...
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Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent
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TN_cdi_proquest_miscellaneous_2091240254
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2091240254
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0140-5