Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a defi...
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
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Full title
Author / Creator
Kong, Xiao-Fei , Martinez-Barricarte, Ruben , Kennedy, James , Mele, Federico , Lazarov, Tomi , Deenick, Elissa K. , Ma, Cindy S. , Breton, Gaëlle , Lucero, Kimberly B. , Langlais, David , Bousfiha, Aziz , Aytekin, Caner , Markle, Janet , Trouillet, Céline , Jabot-Hanin, Fabienne , Arlehamn, Cecilia S. Lindestam , Rao, Geetha , Picard, Capucine , Lasseau, Théo , Latorre, Daniela , Hambleton, Sophie , Deswarte, Caroline , Itan, Yuval , Abarca, Katia , Moraes-Vasconcelos, Dewton , Ailal, Fatima , Ikinciogullari, Aydan , Dogu, Figen , Benhsaien, Ibtihal , Sette, Alessandro , Abel, Laurent , Boisson-Dupuis, Stéphanie , Schröder, Bernd , Nussenzweig, Michel C. , Liu, Kang , Geissmann, Frédéric , Tangye, Stuart G. , Gros, Philippe , Sallusto, Federica , Bustamante, Jacinta and Casanova, Jean-Laurent
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Human inborn errors of IFN-γ immunity underlie mycobacterial diseases. We describe patients with
Mycobacterium bovis
(BCG) disease who are homozygous for loss-of-function mutations of
SPPL2A
. This gene encodes a transmembrane protease that degrades the N-terminal fragment (NTF) of CD74 (HLA invariant chain) in antigen-presenting cells....
Alternative Titles
Full title
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
Authors, Artists and Contributors
Author / Creator
Martinez-Barricarte, Ruben
Kennedy, James
Mele, Federico
Lazarov, Tomi
Deenick, Elissa K.
Ma, Cindy S.
Breton, Gaëlle
Lucero, Kimberly B.
Langlais, David
Bousfiha, Aziz
Aytekin, Caner
Markle, Janet
Trouillet, Céline
Jabot-Hanin, Fabienne
Arlehamn, Cecilia S. Lindestam
Rao, Geetha
Picard, Capucine
Lasseau, Théo
Latorre, Daniela
Hambleton, Sophie
Deswarte, Caroline
Itan, Yuval
Abarca, Katia
Moraes-Vasconcelos, Dewton
Ailal, Fatima
Ikinciogullari, Aydan
Dogu, Figen
Benhsaien, Ibtihal
Sette, Alessandro
Abel, Laurent
Boisson-Dupuis, Stéphanie
Schröder, Bernd
Nussenzweig, Michel C.
Liu, Kang
Geissmann, Frédéric
Tangye, Stuart G.
Gros, Philippe
Sallusto, Federica
Bustamante, Jacinta
Casanova, Jean-Laurent
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2091241779
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2091241779
Other Identifiers
ISSN
1529-2908,1529-2916
E-ISSN
1529-2916
DOI
10.1038/s41590-018-0178-z
