The glutamate homeostasis hypothesis of addiction
The glutamate homeostasis hypothesis of addiction
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Addiction is associated with neuroplasticity in corticostriatal brain circuitry, notably in projections from the prefrontal cortex to the nucleus accumbens.
Repeated drug use impairs the capacity of prefrontal input to the nucleus accumbens to regulate well-established drug-seeking habits originating in motor corticostriatal circui...
Alternative Titles
Full title
The glutamate homeostasis hypothesis of addiction
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TN_cdi_proquest_miscellaneous_20937185
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20937185
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ISSN
1471-003X
E-ISSN
1471-0048,1469-3178
DOI
10.1038/nrn2515
