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Higher than standard dosing regimen are needed to achieve optimal antibiotic exposure in critically...

Higher than standard dosing regimen are needed to achieve optimal antibiotic exposure in critically...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2099040787

Higher than standard dosing regimen are needed to achieve optimal antibiotic exposure in critically ill patients with augmented renal clearance receiving piperacillin-tazobactam administered by continuous infusion

About this item

Full title

Higher than standard dosing regimen are needed to achieve optimal antibiotic exposure in critically ill patients with augmented renal clearance receiving piperacillin-tazobactam administered by continuous infusion

Publisher

United States: Elsevier Inc

Journal title

Journal of critical care, 2018-12, Vol.48, p.66-71

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

To determine whether augmented renal clearance (ARC) impacts negatively on piperacillin-tazobactam unbound concentrations in critically ill patients receiving 16 g/2 g/day administered continuously.
Fifty nine critically ill patients without renal impairment underwent 24-h creatinine clearance (CrCL) measurement and therapeutic drug monitoring d...

Alternative Titles

Full title

Higher than standard dosing regimen are needed to achieve optimal antibiotic exposure in critically ill patients with augmented renal clearance receiving piperacillin-tazobactam administered by continuous infusion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2099040787

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2099040787

Other Identifiers

ISSN

0883-9441

E-ISSN

1557-8615

DOI

10.1016/j.jcrc.2018.08.026

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