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Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways

Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2103678121

Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways

About this item

Full title

Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways

Publisher

Netherlands: Springer

Journal title

Cell stress & chaperones, 2018-11, Vol.23 (6), p.1295-1309

Language

English

Formats

Publication information

Publisher

Netherlands: Springer

More information

Scope and Contents

Contents

Matrine is a natural alkaloid isolated from the root and stem of the legume plant Sophora. Its anti-proliferative and pro-apoptotic effects on several types of cancer have been well-documented. However, the role of matrine in regulating mitochondrial homeostasis, particularly mitophagy in liver cancer apoptosis, remains uncertain. The aim of our st...

Alternative Titles

Full title

Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2103678121

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2103678121

Other Identifiers

ISSN

1355-8145

E-ISSN

1466-1268

DOI

10.1007/s12192-018-0937-7

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