Molecular Imaging Study on In Vivo Distribution and Pharmacokinetics of Modified Small Interfering R...
Molecular Imaging Study on In Vivo Distribution and Pharmacokinetics of Modified Small Interfering RNAs (siRNAs)
About this item
Full title
Author / Creator
Publisher
United States: Mary Ann Liebert, Inc. publishers
Journal title
Language
English
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Publication information
Publisher
United States: Mary Ann Liebert, Inc. publishers
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Scope and Contents
Contents
Molecular imaging was used to study the biodistribution, pharmacokinetics, and activity of naked small interfering RNAs (siRNAs). siRNAs with riboses chemically modified in the 2′ position were compared with unmodified siRNA.
In vitro
, replacement of the 2′-hydroxyl (2′OH) group of certain nucleotides in an siRNA sequence by a fluorine atom...
Alternative Titles
Full title
Molecular Imaging Study on In Vivo Distribution and Pharmacokinetics of Modified Small Interfering RNAs (siRNAs)
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Record Identifier
TN_cdi_proquest_miscellaneous_21039523
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21039523
Other Identifiers
ISSN
1545-4576,2159-3337
E-ISSN
1557-8526,2159-3345
DOI
10.1089/oli.2008.0133
