Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
About this item
Full title
Author / Creator
Huang, Yihe , Winkler, Paige A. , Sun, Weinan , Lü, Wei and Du, Juan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Transient receptor potential melastatin 2 (TRPM2) is a calcium-permeable, non-selective cation channel that has an essential role in diverse physiological processes such as core body temperature regulation, immune response and apoptosis
1
–
4
. TRPM2 is polymodal and can be activated by a wide range of stimuli
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–
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, includ...
Alternative Titles
Full title
Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
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Record Identifier
TN_cdi_proquest_miscellaneous_2112204384
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2112204384
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0558-4
