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All-trans retinoic acid induces COX-2 and prostaglandin E sub(2 )synthesis in SH-SY5Y human neurobla...

All-trans retinoic acid induces COX-2 and prostaglandin E sub(2 )synthesis in SH-SY5Y human neurobla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21232553

All-trans retinoic acid induces COX-2 and prostaglandin E sub(2 )synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2

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Full title

All-trans retinoic acid induces COX-2 and prostaglandin E sub(2 )synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2

Journal title

Journal of neuroinflammation, 2007-01, Vol.4, p.1-1

Language

English

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Scope and Contents

Contents

Background Our recent results show that all-trans retinoic acid (ATRA), an active metabolite of vitamin A, induces COX-dependent hyperalgesia and allodynia in rats. This effect was mediated by retinoic acid receptors (RARs) and was associated with increased COX-2 expression in the spinal cord. Since ATRA also up-regulated COX-2 expression in SH-SY5...

Alternative Titles

Full title

All-trans retinoic acid induces COX-2 and prostaglandin E sub(2 )synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_21232553

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21232553

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/1742-2094-4-1

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