Development of a High-Throughput Cell-Based Assay for 11b-Hydroxysteroid Dehydrogenase Type 1 Using...
Development of a High-Throughput Cell-Based Assay for 11b-Hydroxysteroid Dehydrogenase Type 1 Using BacMam Technology
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English
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Cortisol is an important glucocorticoid in humans that regulates many physiological processes. Human 11b-hydroxysteroid dehydrogenase type 1 (11b-HSD1) converts cortisone to cortisol invivo and has emerged as an appealing therapeutic target for treating metabolic diseases. Here, we report a sensitive and robust high-throughput (HT) cell-based assay...
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Development of a High-Throughput Cell-Based Assay for 11b-Hydroxysteroid Dehydrogenase Type 1 Using BacMam Technology
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TN_cdi_proquest_miscellaneous_21300365
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21300365
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ISSN
1073-6085
E-ISSN
1559-0305
DOI
10.1007/s12033-008-9050-y
