Defective survival of naive CD8 super(+) T lymphocytes in the absence of the b3 regulatory subunit o...
Defective survival of naive CD8 super(+) T lymphocytes in the absence of the b3 regulatory subunit of voltage-gated calcium channels
About this item
Full title
Defective survival of naive CD8 super(+) T lymphocytes in the absence of the b3 regulatory subunit of voltage-gated calcium channels
Author / Creator
Journal title
Nature immunology, 2009-12, Vol.10 (12), p.1275-1282
Language
English
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Scope and Contents
Contents
The survival of T lymphocytes requires sustained, Ca super(2+) influx-dependent gene expression. The molecular mechanism that governs sustained Ca super(2+) influx in naive T lymphocytes is unknown. Here we report an essential role for the b3 regulatory subunit of voltage-gated calcium (Ca sub(v)) channels in the maintenance of naive CD8 super(+) T...
Alternative Titles
Full title
Defective survival of naive CD8 super(+) T lymphocytes in the absence of the b3 regulatory subunit of voltage-gated calcium channels
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_21317891
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21317891
Other Identifiers
ISSN
1529-2908
DOI
10.1038/ni.1793
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