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Reduction of arginase I activity and manganese levels in the liver during exposure of rats to methyl...

Reduction of arginase I activity and manganese levels in the liver during exposure of rats to methyl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21338634

Reduction of arginase I activity and manganese levels in the liver during exposure of rats to methylmercury: a possible mechanism

About this item

Full title

Reduction of arginase I activity and manganese levels in the liver during exposure of rats to methylmercury: a possible mechanism

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

Journal title

Archives of toxicology, 2008-11, Vol.82 (11), p.803-808

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

The toxicity of methylmercury (MeHg) is, in part, thought to be due to its interaction with thiol groups in a variety of enzymes, but the molecular targets of MeHg are poorly understood. Arginase I, an abundant manganese (Mn)-binding protein in the liver, requires Mn as an essential element to exhibit maximal enzyme activity. In the present study,...

Alternative Titles

Full title

Reduction of arginase I activity and manganese levels in the liver during exposure of rats to methylmercury: a possible mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_21338634

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21338634

Other Identifiers

ISSN

0340-5761

E-ISSN

1432-0738

DOI

10.1007/s00204-008-0307-9

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