Dynamic molecular monitoring reveals that SWI–SNF mutations mediate resistance to ibrutinib plus ven...
Dynamic molecular monitoring reveals that SWI–SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma
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Full title
Author / Creator
Agarwal, Rishu , Chan, Yih-Chih , Tam, Constantine S. , Hunter, Tane , Vassiliadis, Dane , Teh, Charis E. , Thijssen, Rachel , Yeh, Paul , Wong, Stephen Q. , Ftouni, Sarah , Lam, Enid Y. N. , Anderson, Mary Ann , Pott, Christiane , Gilan, Omer , Bell, Charles C. , Knezevic, Kathy , Blombery, Piers , Rayeroux, Kathleen , Zordan, Adrian , Li, Jason , Huang, David C. S. , Wall, Meaghan , Seymour, John F. , Gray, Daniel H. D. , Roberts, Andrew W. , Dawson, Mark A. and Dawson, Sarah-Jane
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Ibrutinib plus venetoclax is a highly effective combination in mantle cell lymphoma. However, strategies to enable the evaluation of therapeutic response are required. Our prospective analyses of patients within the AIM study revealed genomic profiles that clearly dichotomized responders and nonresponders. Mutations in
ATM
were present in mos...
Alternative Titles
Full title
Dynamic molecular monitoring reveals that SWI–SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma
Authors, Artists and Contributors
Author / Creator
Chan, Yih-Chih
Tam, Constantine S.
Hunter, Tane
Vassiliadis, Dane
Teh, Charis E.
Thijssen, Rachel
Yeh, Paul
Wong, Stephen Q.
Ftouni, Sarah
Lam, Enid Y. N.
Anderson, Mary Ann
Pott, Christiane
Gilan, Omer
Bell, Charles C.
Knezevic, Kathy
Blombery, Piers
Rayeroux, Kathleen
Zordan, Adrian
Li, Jason
Huang, David C. S.
Wall, Meaghan
Seymour, John F.
Gray, Daniel H. D.
Roberts, Andrew W.
Dawson, Mark A.
Dawson, Sarah-Jane
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2136068677
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2136068677
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0243-z