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A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recogn...

A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recogn...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2136068688

A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions

About this item

Full title

A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions

Publisher

London: Nature Publishing Group UK

Journal title

Nature microbiology, 2019-01, Vol.4 (1), p.71-77

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

West Nile virus (WNV), a member of the
Flavivirus
genus, is a leading cause of viral encephalitis in the United States
1
. The development of neutralizing antibodies against the flavivirus envelope (E) protein is critical for immunity and vaccine protection
2
. Previously identified candidate therapeutic mouse and human neutralizi...

Alternative Titles

Full title

A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2136068688

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2136068688

Other Identifiers

ISSN

2058-5276

E-ISSN

2058-5276

DOI

10.1038/s41564-018-0283-7

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