Berberine chloride mediates its antileishmanial activity by inhibiting Leishmania mitochondria
Berberine chloride mediates its antileishmanial activity by inhibiting Leishmania mitochondria
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
Berberine chloride, a plant-derived isoquinoline alkaloid, has been demonstrated to have leishmanicidal activity, which is mediated by generation of a redox imbalance and depolarization of the mitochondrial membrane, resulting in a caspase-independent apoptotic-like cell death. However, its impact on mitochondrial function remains to be delineated...
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Full title
Berberine chloride mediates its antileishmanial activity by inhibiting Leishmania mitochondria
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Record Identifier
TN_cdi_proquest_miscellaneous_2137469633
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2137469633
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ISSN
0932-0113,1432-1955
E-ISSN
1432-1955
DOI
10.1007/s00436-018-6157-3
