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A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and suc...

A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and suc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2138648929

A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate

About this item

Full title

A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2019-01, Vol.25 (1), p.75-81

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Understanding the mechanisms underlying autoantibody development will accelerate therapeutic target identification in autoimmune diseases such as systemic lupus erythematosus (SLE)
1
. Follicular helper T cells (T
FH
cells) have long been implicated in SLE pathogenesis. Yet a fraction of autoantibodies in individuals with SLE are unmuta...

Alternative Titles

Full title

A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2138648929

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2138648929

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-018-0254-9

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