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Structure of native lens connexin 46/50 intercellular channels by cryo-EM

Structure of native lens connexin 46/50 intercellular channels by cryo-EM

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2155929794

Structure of native lens connexin 46/50 intercellular channels by cryo-EM

About this item

Full title

Structure of native lens connexin 46/50 intercellular channels by cryo-EM

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2018-12, Vol.564 (7736), p.372-377

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Gap junctions establish direct pathways for cell-to-cell communication through the assembly of twelve connexin subunits that form intercellular channels connecting neighbouring cells. Co-assembly of different connexin isoforms produces channels with unique properties and enables communication across cell types. Here we used single-particle cryo-ele...

Alternative Titles

Full title

Structure of native lens connexin 46/50 intercellular channels by cryo-EM

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2155929794

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2155929794

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0786-7

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