Myeloid immune-checkpoint inhibition enters the clinical stage
Myeloid immune-checkpoint inhibition enters the clinical stage
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The first-in-human study of anti-CD47 antibodies blocking CD47–SIRPα interactions in combination with rituximab in patients with non-Hodgkin lymphoma shows encouraging clinical responses accompanied with mild levels of toxicity. Inhibition of the CD47–SIRPα interaction might provide a generic method of promoting the effects of antitumour antibodies...
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Full title
Myeloid immune-checkpoint inhibition enters the clinical stage
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TN_cdi_proquest_miscellaneous_2159983892
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2159983892
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ISSN
1759-4774
E-ISSN
1759-4782
DOI
10.1038/s41571-018-0155-3