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Myeloid immune-checkpoint inhibition enters the clinical stage

Myeloid immune-checkpoint inhibition enters the clinical stage

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2159983892

Myeloid immune-checkpoint inhibition enters the clinical stage

About this item

Full title

Myeloid immune-checkpoint inhibition enters the clinical stage

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Clinical oncology, 2019-05, Vol.16 (5), p.275-276

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The first-in-human study of anti-CD47 antibodies blocking CD47–SIRPα interactions in combination with rituximab in patients with non-Hodgkin lymphoma shows encouraging clinical responses accompanied with mild levels of toxicity. Inhibition of the CD47–SIRPα interaction might provide a generic method of promoting the effects of antitumour antibodies...

Alternative Titles

Full title

Myeloid immune-checkpoint inhibition enters the clinical stage

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2159983892

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2159983892

Other Identifiers

ISSN

1759-4774

E-ISSN

1759-4782

DOI

10.1038/s41571-018-0155-3

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