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The cGMP-Degrading Enzyme Phosphodiesterase-5 (PDE5) in Cerebral Small Arteries of Older People

The cGMP-Degrading Enzyme Phosphodiesterase-5 (PDE5) in Cerebral Small Arteries of Older People

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2161700997

The cGMP-Degrading Enzyme Phosphodiesterase-5 (PDE5) in Cerebral Small Arteries of Older People

About this item

Full title

The cGMP-Degrading Enzyme Phosphodiesterase-5 (PDE5) in Cerebral Small Arteries of Older People

Publisher

England: Oxford University Press

Journal title

Journal of neuropathology and experimental neurology, 2019-02, Vol.78 (2), p.191-194

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Abstract
Cerebral small vessel disease in deep penetrating arteries is a major cause of lacunar infarcts, white matter lesions and vascular cognitive impairment. Local cerebral blood flow in these small vessels is controlled by endothelial-derived nitric oxide, which exerts a primary vasodilator stimulus on vascular myocytes, via cytoplasmic cyc...

Alternative Titles

Full title

The cGMP-Degrading Enzyme Phosphodiesterase-5 (PDE5) in Cerebral Small Arteries of Older People

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2161700997

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2161700997

Other Identifiers

ISSN

0022-3069,1554-6578

E-ISSN

1554-6578

DOI

10.1093/jnen/nly117

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