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Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational...

Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2162498182

Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids

About this item

Full title

Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids

Publisher

Tokyo: Springer Japan

Journal title

Journal of gastroenterology, 2019-07, Vol.54 (7), p.608-620

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Japan

More information

Scope and Contents

Contents

Background
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with an intractable, recurrent course. The goal of UC therapy is to target mucosal healing because immune-suppressive therapy for UC frequently results in relapse. However, few drugs directly target mucosal healing. We, therefore, aim to evaluate the therapeutic ef...

Alternative Titles

Full title

Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2162498182

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2162498182

Other Identifiers

ISSN

0944-1174

E-ISSN

1435-5922

DOI

10.1007/s00535-018-01540-y

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