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Challenges in unsupervised clustering of single-cell RNA-seq data

Challenges in unsupervised clustering of single-cell RNA-seq data

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2165100125

Challenges in unsupervised clustering of single-cell RNA-seq data

About this item

Full title

Challenges in unsupervised clustering of single-cell RNA-seq data

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Genetics, 2019-05, Vol.20 (5), p.273-282

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Single-cell RNA sequencing (scRNA-seq) allows researchers to collect large catalogues detailing the transcriptomes of individual cells. Unsupervised clustering is of central importance for the analysis of these data, as it is used to identify putative cell types. However, there are many challenges involved. We discuss why clustering is a challengin...

Alternative Titles

Full title

Challenges in unsupervised clustering of single-cell RNA-seq data

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2165100125

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2165100125

Other Identifiers

ISSN

1471-0056

E-ISSN

1471-0064

DOI

10.1038/s41576-018-0088-9

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